Anne K. Dunn, Ph.D.

Chair, Associate Professor
712, George Lynn Cross
770 Van Vleet Oval
Norman, OK 73019
405-325-6302 (Office)
405-325-5762 (Lab)
akdunn@ou.edu 

B.S., Biology, Iowa State University, 1996
PhD, Bacteriology, University of Wisconsin, 2002
Postdoc, University of Georgia, 2002-2007

 

Research areas:  Microbiology, Molecular and Cellular Biology, Anaerobic Microbiology, Aerobic Microbiology, Beneficial Host-Microbe Interactions, Microbial Physiology

Research interests:

The Dunn lab uses molecular and genetic tools to understand how bacterial physiology contributes to the ability of microbes to survive and thrive in the environment, whether while free-living or during association with another organism. Our current model organism is the bioluminescent marine bacterium Vibrio fischeri. This organism has both a free-living and a symbiotic host-associated lifestyle, making it an ideal organism for studying how different physiological attributes contribute to flexibility in lifestyle. V. fischeri has diverse pathways for energy conservation, and the lab is interested in understanding how these pathways contribute to both host colonization and survival outside of the host. Through these studies we have become interested in the unusual respiratory oxidase, alternative oxidase (AOX). We are currently using the wealth of molecular and genetic tools in V. fischeri to better understand how AOX function physiologically benefits bacteria.

Relevant publications:

Septer, A.N., Y. Wang, E.G. Ruby, E.V. Stabb, and A.K. Dunn. 2011. The heme-uptake gene cluster in Vibrio fischeri is regulated by Fur and contributes to symbiotic colonization. Environ. Microbiol. 13:2855-2864.

Wang, Y., A.K. Dunn, J. Wilneff, M.J. McFall-Ngai, S. Spiro, and E.G. Ruby. 2010. Vibrio fischeri Flavohemoglobin is the Key NO-Detoxification System during Initiation of the Squid-Vibrio Symbiosis. Mol. Microbiol. 78:903-915.

Dunn, A.K., E.A. Karr, Y. Wang, A.R. Batton, E.G. Ruby, and E.V. Stabb. 2010. The alternative oxidase (AOX) gene in Vibrio fischeri is controlled by NsrR and upregulated in response to nitric oxide. Mol. Microbiol. 77:44-55.

Dunn, A.K., and E.V. Stabb. 2008 Genetic analysis of trimethylamine N-oxide reductases in the light-organ symbiont Vibrio fischeri ES114. J. Bacteriol. 190:5814-5823.

Dunn, A.K., D. S. Millikan, D.S. Adin, J.L. Bose, and E.V. Stabb. 2006. New rfp- and pES213-derived tools for analyzing symbiotic Vibrio fischeri reveal patterns of infection and lux expression in situ. Appl. Environ. Microbiol. 72:802-810.



 

Contact Us
Phone 405-325-4321
770 Van Vleet Oval

Norman, OK 73019
136 George Lynn Cross Hall
Hours: 8:00 am - 
5:00 pm M-F           Closed For Lunch 12:00 - 1:00
Directions

Follow us on Facebook