219 George Lynn Cross Hall
770 Van Vleet Oval
Norman, OK 73019
B.Sc. Frostburg State University, 1990
M. Sc., Ohio University, 1996
PhD, Biology, UNC-Chapel Hill, 2002
Postdoc, UNC-Chapel Hill, 2002-2006
Research Areas: Plant Biology, Molecular, Cellular and Developmental Biology, Evolutionary Biology
My research focuses on the molecular regulation of transitional events during plant development and stress responses. I am particularly interested in mechanistically describing gene expression as a result of variable environmental inputs, such as changes in day length. Members of my lab are experimentally addressing these areas of interest as they relate to the functions of three interacting transcription factor families called NUCLEAR FACTOR Y (NF-Y). Specific examples include NF-Y functions in photoperiod-dependent flowering time and during responses to the phytohormone abscisic acid. Although our primary approach is discovery through traditional genetic analyses, we take full advantage of modern molecular, biochemical, and in silica techniques to help describe the mechanistics of NF-Y function.
Kumimoto RW, Siriwardana CL, Gayler KK, Risinger JR, Siefers N, et al. 2013. NUCLEAR FACTOR Y transcription factors have both opposing and additive roles in ABA-mediated seed germination. PLoS ONE 8(3): e59481.
Petroni, K., R.W. Kumimoto, N. Gnesutta, V. Calvenzani, C. Tonelli, B.F. Holt III, R. Mantovani. 2012. The promiscuous life of plant NUCLEAR FACTOR Y (NF-Y) transcription factors. The Plant Cell, 24: 4777–4792.
Cao, S., R.W. Kumimoto, C.L. Siriwardana, J.R. Risinger, and B.F. Holt III. 2011. Identification and characterization of NF-Y transcription factor families in the monocot model plant Brachypodium distachyon. PloS One, 6:e21805.
Kumimoto, R., Y. Zhang, N. Siefers, and B.F. Holt III. 2010. NF-YC3, NF-YC4, and NF-YC9 are required for CONSTANS-mediated, photoperiod-dependent flowering in Arabidopsis thaliana. Plant Journal, 63: 379-391.
Siefers, N., K. Dang, R. Kumimoto, W.E. Bynum, G. Tayrose, and B.F. Holt III. 2009. Tissue specific expression patterns of Arabidopsis thaliana NF-Y transcription factors suggest potential for extensive combinatorial complexity. Plant Physiology, 149: 625-641.